e -Issn : 0976 - 3651
Print-Issn : 2229-7480

  ABSTRACT

ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF LEAF EXTRACTS OF FOUR COMMON PLANTS

The aim of the work was to screen the phytochemical constituents, antioxidant and antimicrobial activity of water, ethanol and chloroform extract of leaves of plants Annona squamosa, Mentha spicata, Tamarindus indica, Moringa oleifera, from two different areas (Akkayyapalem, Sabbavaram Kota). And the antimicrobial activity was measured by agar well diffusion method; the diameter of the zone of bacterial and fungal growth inhibition was measured after incubation of plates. The inhibitory effect was studied against the pathogenic bacteria (Escherichia coli, Bacillus subtilis, Klebsiella pneumoniae, Proteus vulgaris, Staphylococcus aureus) and fungi (Apsergillus, Mucor, Geotricum). Antioxidant assays were also performed for the same extracts by spectrophotometric methods using known standard antioxidants as reference. All the studied plants were found to be very effective against the pathogenic microorganisms tested. And the ethanolic extract of Annona squmosa from Sabbavaram Kota area showed maximum activity against Escherichia coli and Staphylococcus aureus. And the least concentration required showing the activity was 0.156mg/ml. Phytochemical screening of the plants revealed the presence of tannins, flavonoids, saponins and alkaloids. Good presence of antioxidants was also found in all the plants. The antioxidant activity was found higher in Tamarindus indica followed by Mentha spicata, Annona squamosa and Moringa oleifera.

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