ANTIFERTILITY EFFECT OF CARICA PAPAYA LINN. SEED EXTRACT ON HORMONES IN MALE ALBINO RATS
The effect of Carica papaya Linn. (Paw-paw) seed extract on gonadotrophic hormone levels and testosterone levels in control and Carica papaya seed extract administered albino rats was studied. Administration of papaya seed extract (150mg/kg body wt/day for 15 days) to Wistar male rat through oral route affected the reproductive hormone levels. Due to the low levels of testosterone, the hypothalamo- hypopysial axis was inhibited and there by accumulation of gonadotropins was noticed. The hyper gonadotropins noticed in the present study may be due to hypo testosterone levels. Thus, the C. papaya seed extract affect on the hormonal synthesis and their function which leads to infertility