e -Issn : 0976 - 3651
Print-Issn : 2229-7480

  ABSTRACT

EFFECT OF FICUS RELIGIOSA PHENOLICS ON THE FORMATION OF BIOFILM AND SWARMING OF PROTEUS MIRABILIS

Urinary tract infection by Proteus mirabilis depends on several virulence properties such as ability of adherence and swarming. Here we report the antiadherence, antibiofilm and antiswarming effects of phenolic compounds of Ficus religiosa leaves and bark. The results showed that phenolic compounds of leaves was more effected than bark in reduction of adherence, biofilm formation and swarming motility especially at concentration 2 mg/ml , the reduction of adherence of bacteria was obvious in glass tubes. The ability of leaves phenolics to decreasing the biofilm formation in microtiter plate was significant in contrast with control. The results which suggests that Ficus religiosa phenolics can potentially be developed as UTI drugs

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