ANTI-INFLAMMATORY ACTIVITY OF THE SIMPLE ASCIDIAN, PHALLUSIA ARABICA SAVIGNY
The present study investigates the acute and chronic anti-inflammatory activity in ethanolic extract of the simple ascidian Phallusia arabica. The reduction in paw volume was highly significant in Group V treated with 400 mg/kg bw followed by Group IV (200mg/kg bw), indicating a dose dependent activity compared to control. Studies on biochemical parameters of the serum, liver and exudates indicated lower lipid peroxide content and γ -glutamyl transpeptidase activity. Results showed that ethanolic extract of the Phallusia arabica had potent and significant anti-inflammatory activity