EVALUATION OF IN-VIVO ANTI-DIARRHOEAL ACTIVITY OF PROSOPIS CINERARIA LINN STEM BARK
In the present study, in vivo antidiarrhoeal studies were performed on the stem barks of Prosopis cineraria (Mimosaceae). Methanolic extract of the drug were evaluated for in vivo antidiarrhoeal activity, used experimental induced diarrhoea models are Castor-oil induced diarrhoea and Charcoal induced gastrointestinal motility test in rats. Pre-treatment with methanolic extract of Prosopis cineraria at the doses (150 and 300 mg/kg.p.o) were administered through the oral route. The plant extracts exhibited dose dependent antidiarrhoeal effects in the all treated groups and the results were compared with that of loperamide (1mg/kg, p.o) as reference standard drug. This study confirmed the use of plant stem barks as an antidiarrhoeal agent.