DENDRIMER: NOVEL DRUG DELIVERY SYSTEM A REVIEW
Dendrimer as a drug delivery agent is a promising, safe and selective drug delivery method. It has highly selective nature for targeting the desired tissue is the most essential property. It is having promising future for the treatment of several disorders. And also it having other properties like very small in size, polyvalency, monodispersity, good stability makes it a good carrier for delivering drugs with precision and selectivity. Dendrimers are being used as drug delivery systems for many drugs like anticancer drugs, anti tubercular drugs, enhancing bioavailability of pilocarpine for ocular drug delivery. Dendrimer as a drug delivery system is based on the approach of injecting a nanoparticle (10-9) to the body, loaded with drug. The drug might be loaded on its encapsulated within the branches or terminal surface of a dendrimer. Dendrimers generally used to increased bioavailability especially sustained, controlled and targeted release of drug and there is reduction in the amount of drug and systemic toxicity while the therapeutic efficacy is increases. Thus present review focuses on the fundamentals of dendrimers and their use as drug delivery agents in treatment of various disorders.