EVALUATION OF ANTI-INFLAMMATORY ACTIVITY OF BUCHANANIA AXILLARIS (DESR.) LEAVES
Aim of the study to evaluate the anti-inflammatory activity of the leaves of Buchanania axillaris. Anti-inflammatory activity was conducted by using Carrageenan induced rat paw oedema model. The thickness of paws of rats was measured every hour up to 5 hrs for methanolic extract at doses of 100, 200 and 400mg/kg by volume displacement method, using plethysmometer. All doses of the extract (methanol) from the leaves of Buchanania axillaris showed significant percentage of inhibition on Carrageenan induced paw oedema; methanol extract from the leaves of Buchanania axillaris at dose 400mg/kg produced significant (P<0.001) percentage of inhibition when compared to other doses. Buchanania axillaris leaves extract (methanol), showed significant anti-inflammatory activity.