MICROWAVE MEDIATED SYNTHESIS OF SOME DIARYL PIPERIDINE-4-ONE DERIVATIVES
A series of Diaryl piperidine-4-one Derivatives were synthesized by using microwave irradiation .The synthesis involves microwave irradiation of Ammonium acetate with montmorinollite K – 10 in a dry condition. Freshly distilled aromatic aldehyde, and ketone was added to the above mixture and then heated until colour of the solution turned yellow and left at room temperature overnight. The reaction was completed in 6-12 hrs with 40-50% yields and was environmentally friendly with easy to workup. The synthesized compounds were evaluated and its M.P’s were determined.