IN VITRO ANTIOXIDANT AND ANTIGENOTOXIC POTENTIAL OF ETHANOLIC EXTRACT OF CALLISTAMONE CITRINUS FLOWER
Ethanolic extract of Callistemon citrinus flower was prepared and assessed in vitro for its phytochemical composition, and antioxidant potentials. It was specially assessed for its DNA damage inhibitory potential by using goat liver DNA as model system. Callistamone citrinus ethanolic extract showed good activity in all the tests carried out even in low concentrations. Study revealed the presence of saponin, flavanoid, terepenoids and tannin as major phytoconstituents as well as it reflected potent antioxidant activity in all the in vitro assays. It showed a concentration dependent increase in antioxidant potential. Moreover extract showed a good potential of inhibition of DNA damage. Results suggested the assessment of callistemon citrinus fractions in in vivo systems to develop therapeutic molecules for oxidative stress