FORMULATION AND EVALUATION FOR INVITRO DISSOLUTION STUDIES OF COLON TARGETED MICROSPHERES OF CAPECITABINE
Capecitabine microspheres are prepared as colon targeted microspheres. These were prepared by using with the sodium alginate as a polymer with different concentrations such as 4%, 5%, 6% concentrations. These prepared microspheres are filled in the EudragitS-100 coated capsules. And these microspheres were evaluated for physical characterization and in vitro dissolution studies. From the in vitro dissolution studies the 4% formulation showed good results among the other formulations