PHYTOCONSTITUENTS WITH ANTIUROLITHIC ACTIVITY-A REVIEW
Urolithiasis is the condition where urinary calculi are formed in the urinary tract. Renal stone disease happens to be one of the major causes of chronic kidney disease and chronic renal failure. Stone formation is documented from traditional periods and is considered as a medical challenge due to its multifactorial etiology. Kidney stone formation or urolithiasis is a complex process that results from a succession of several physicochemical events including supersaturation, nucleation, growth, aggregation, and retention within the kidneys. Epidemiological data have shown that calcium oxalate is the predominant mineral in a majority of kidney stones. Among the treatments used are extracorporeal shock wave lithotripsy (ESWL) and drug treatment. Even improved and besides the high cost that imposes, compelling data now suggest that exposure to shock waves in therapeutic doses may cause acute renal injury, decrease in renal function and an increase in stone recurrence. In addition, persistent residual stone fragments and the possibility of infection after ESWL represent a serious problem in the treatment of stones. Furthermore, in spite of substantial progress in the study of the biological and physical manifestations of kidney stones, there is no satisfactory drug to use in clinical therapy. As investigations proved that phytotherapy is potent in preventing and curing renal calculi with less side effects and also produced satisfactory results in preventing reoccurrence of renal stones so, the present article is mainly focused on providing information on potent herbal wealth with litho lytic property