INTERLEUKIN-2 LEVEL IN WOMEN WITH NON INFECTIOUS RECURRENT ABORTION AND HEALTHY PREGNANT AND NON PREGNANT WOMEN IN IRAQ USING ELIZA TECHNIQUE
Spontaneous abortion is the most common complication of pregnancy. it might happen under the effect of many causes including environmental pollution. During the last few decades environmental pollution in Iraq with physical, chemical, and biological pollutants has been associated with increased percentage of some disease like cancer, recurrent abortion, autoimmune disease, respiratory disease…..etc. IL-2 has been used as immune parameter because of its role concerning allograft rejection and spontaneous recurrent abortion (SRA), so the present study aimed to estimate IL-2 level in group of women with non infectious recurrent abortion beside a group of healthy control women. A total of 55 Iraqi women grouped as 35 non infectious recurrently aborted women and with normal health history beside 10 non pregnant and 10 pregnant women as healthy control were used in the present study. Serum IL-2 level was estimated using sandwich method ELISA technique. The mean level of IL-2 was (315.41 ± 38.84) pg/ ml, (36.48 ± 13.19) pg/ ml and (118.63 ± 24.81) pg/ ml in patients, control non pregnant and control pregnant women respectively with presence of statistically significant difference among different groups. This result include the control healthy women a fact that need more investigations .Our conclusion suggested alteration of some immune cells function which might result from chronic exposure to some type of environmental pollution which lead to cytokine imbalance and outcome of SRA