e -Issn : 0976 - 3651
Print-Issn : 2229-7480

  ABSTRACT

EXPLORING THE ETHANOLIC EXTRACT OF NEPHROLEPIS CORDIFOLIA LEAF FOR THE IN VITRO ACTIVITY OF MEMBRANE STABILIZATION AND PROTEIN DENATURATION ASSAY

The present study deals with inspecting the inhibitory activity on ethanolic extract leaves of, Nephrolepis cordifolia. To inquire about the membrane stabilization and protein denaturation assay in the leaf of Nephrolepis cordifolia. Membrane stabilization and protein denaturation assay at varying concentrations. Denaturation of protein is one of the well-documented causes of Inflammation. Denaturation leads breakdown of various bonds that exist within a molecule and macromolecule. Membrane stabilization is the blocking action potential across nerve cells thereby producing a nerve block. The IC50 values of ethanolic leaf extract Nephrolepsis cordifolia was 68.97?g/ml and 7.48 ?g/ml for protein denaturation and membrane stabilization assay. This study suggests ethanolic leaf extract Nephrolepsis cordifolia effectively produce Anti – Rheumatoid activity

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